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Pyrexia of Unknown Origin

Systematic investigation of prolonged unexplained fevers with targeted diagnostics at Arete Hospitals, Hyderabad.

Pyrexia of unknown origin
Fever Specialist 16+ Years Experience Arete Hospitals OPD

Overview

Pyrexia of unknown origin (PUO) refers to prolonged fever without an established diagnosis despite initial evaluation. It requires a methodical, stepwise approach to uncover infections, malignancies, autoimmune conditions, and other hidden causes.

Dr. Sandeep Reddy applies structured PUO protocols — combining detailed clinical reasoning with targeted investigations — to identify the source of fever and initiate appropriate treatment at Arete Hospitals.

Conditions We Treat

  • Classic PUO (Fever > 3 Weeks)
  • Nosocomial & Healthcare-Associated Fever
  • HIV-Associated PUO
  • Tropical & Travel-Related Fevers
  • Drug-Induced & Factitious Fever
  • Recurrent Undiagnosed Fever Episodes

Our Treatment Approach

  1. Detailed Fever History

    Pattern analysis, travel and exposure history, medication review, and prior investigation audit.

  2. Structured Workup

    Baseline blood tests, cultures, imaging, and serology guided by clinical probability — avoiding unnecessary testing.

  3. Differential Diagnosis

    Systematic evaluation for infections, malignancy, connective tissue disease, and granulomatous disorders.

  4. Targeted Treatment

    Empiric therapy only when indicated, with close monitoring and reassessment until definitive diagnosis is reached.

Why Choose Dr. Sandeep Reddy

  • Methodical PUO evaluation with clinical reasoning expertise
  • Experience with tropical, endemic, and travel-related fevers
  • Rational use of diagnostics — focused, not exhaustive
  • Integrated infectious disease and autoimmune disease perspective
  • Persistent follow-up until diagnosis and resolution

Find the Cause of Your Fever

Unexplained fever deserves expert investigation. Book a PUO consultation with Dr. Sandeep Reddy at Arete Hospitals.